Correction of errors in tandem mass spectrum extraction enhances phosphopeptide identification

The tandem mass spectrum extraction of phosphopeptides is more difficult and error-prone than that of unmodified peptides due to their lower abundance, lower ionization efficiency, the cofragmentation with other high-abundance peptides, and the use of MS3 on MS2 fragments with neutral losses. Howeve...

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Bibliographic Details
Main Authors: Hao, Piliang, Ren, Yan, Sze, Siu Kwan, Tam, James P.
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2014
Subjects:
Online Access:https://hdl.handle.net/10356/103597
http://hdl.handle.net/10220/19341
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Institution: Nanyang Technological University
Language: English