Profiling the 'deamidome' of complex biosamples using mixed-mode chromatography-coupled tandem mass spectrometry
Deamidation is a spontaneous degenerative protein modification (DPM) that disrupts the structure and function of both endogenous proteins and various therapeutic agents. While deamidation has long been recognized as a critical event in human aging and multiple degenerative diseases, research progres...
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| Main Authors: | , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2022
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/161729 |
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| Institution: | Nanyang Technological University |
| Language: | English |