Synthesis, Characterization, and Biological Properties of Osmium-Based Tamoxifen Derivatives - Comparison with Their Homologues in the Iron and Ruthenium Series

Three osmium analogues 3a–3c of hydroxytamoxifen were prepared. The antiproliferative effects of these complexes were measured against two breast cancer cell lines (MCF-7 and MDA-MB-231) and compared with those of their homologues of ferrocene (1a–1c) and ruthenocene (2a–2c). The tamoxifen-like comp...

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Bibliographic Details
Main Authors: Lee, Hui Zhi Shirley, Buriez, Olivier, Chau, François, Labbé, Eric, Ganguly, Rakesh, Amatore, Christian, Jaouen, Gérard, Vessières, Anne, Leong, Weng Kee, Top, Siden
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2015
Subjects:
Online Access:https://hdl.handle.net/10356/103650
http://hdl.handle.net/10220/38791
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Institution: Nanyang Technological University
Language: English