Ferrocenyl catechols : synthesis, oxidation chemistry and anti-proliferative effects on MDA-MB-231 breast cancer cells

• Main Authors: Hillard, Elizabeth A., Tan, Kelvin Yong Leng, Pigeon, Pascal, Top, Siden, Labbé, Eric, Buriez, Olivier, Vessières, Anne, Amatore, Christian, Leong, Weng Kee, Jaouen, Gérard
• 其他作者: School of Physical and Mathematical Sciences
• 格式: Article
• 語言: English
• 出版: 2013
• 在線閱讀: https://hdl.handle.net/10356/96342; http://hdl.handle.net/10220/10868
• 機構: Nanyang Technological University

The synthesis and anti-tumoral properties of a series of compounds possessing a ferrocenyl group tethered to a catechol via a conjugated system is presented. On MDA-MB-231 breast cancer cell lines, the catechol compounds display a similar or greater anti-proliferative potency (IC50 values ranging fr...