Young capillary vessels rejuvenate aged pancreatic islets

• Main Authors: Almaça, Joana, Molina, Judith, Arrojo e Drigo, Rafael, Abdulreda, Midhat H., Jeon, Won Bae, Berggren, Per-Olof, Caicedo, Alejandro, Nam, Hong Gil
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2015
• Subjects: DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/103728; http://hdl.handle.net/10220/24588
• Institution: Nanyang Technological University

Pancreatic islets secrete hormones that play a key role in regulating blood glucose levels (glycemia). Age-dependent impairment of islet function and concomitant dysregulation of glycemia are major health threats in aged populations. However, the major causes of the age-dependent decline of islet fu...