Detection of outlier residues for improving interface prediction in protein heterocomplexes

• المؤلفون الرئيسيون: Chen, Peng, Wong, Limsoon, Li, Jinyan
• مؤلفون آخرون: School of Computer Engineering
• التنسيق: مقال
• اللغة: English
• منشور في: 2013
• الموضوعات: DRNTU::Engineering::Computer science and engineering::Computer applications::Life and medical sciences
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/103829; http://hdl.handle.net/10220/16551
• المؤسسة: Nanyang Technological University

Sequence-based understanding and identification of protein binding interfaces is a challenging research topic due to the complexity in protein systems and the imbalanced distribution between interface and noninterface residues. This paper presents an outlier detection idea to address the redundancy...