Detection of outlier residues for improving interface prediction in protein heterocomplexes

• Main Authors: Chen, Peng, Wong, Limsoon, Li, Jinyan
• Other Authors: School of Computer Engineering
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Engineering::Computer science and engineering::Computer applications::Life and medical sciences
• Online Access: https://hdl.handle.net/10356/103829; http://hdl.handle.net/10220/16551
• Institution: Nanyang Technological University

Sequence-based understanding and identification of protein binding interfaces is a challenging research topic due to the complexity in protein systems and the imbalanced distribution between interface and noninterface residues. This paper presents an outlier detection idea to address the redundancy...