Chaperone-mediated autophagy : roles in disease and aging

This review focuses on chaperone-mediated autophagy (CMA), one of the proteolytic systems that contributes to degradation of intracellular proteins in lysosomes. CMA substrate proteins are selectively targeted to lysosomes and translocated into the lysosomal lumen through the coordinated action of...

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Bibliographic Details
Main Authors: Cuervo, Ana Maria, Wong, Esther
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2015
Subjects:
Online Access:https://hdl.handle.net/10356/103863
http://hdl.handle.net/10220/25498
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Institution: Nanyang Technological University
Language: English