Knockdown effects of CHIP and UCH-L1 on chaperone-mediated autophagy.
Chaperone-mediated autophagy (CMA) is a selective form of autophagy which degrades cytosolic proteins bearing a CMA-targeting motif. CMA is carried out by chaperone proteins and aberrant CMA function has been implicated in disease. Its physiological regulation is not well understood, which is import...
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Format: | Final Year Project |
Language: | English |
Published: |
2013
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Online Access: | http://hdl.handle.net/10356/52700 |
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Institution: | Nanyang Technological University |
Language: | English |