β-functionalization of carboxylic anhydrides with β-alkyl substituents through carbene organocatalysis

The first NHC-catalyzed functionalization of carboxylic anhydrides is described. In this reaction, the β carbon behaves as a nucleophilic carbon and undergoes asymmetric reactions with electrophiles. Anhydrides with challenging β-alkyl substituents work effectively.

Saved in:

Bibliographic Details
Main Authors:	Jin, Zhichao, Chen, Shaojin, Wang, Yuhuang, Zheng, Pengcheng, Yang, Song, Chi, Robin Yonggui
Other Authors:	School of Physical and Mathematical Sciences
Format:	Article
Language:	English
Published:	2015
Subjects:	DRNTU::Science::Chemistry::Organic chemistry::Carbanions DRNTU::Science::Chemistry::Physical chemistry::Catalysis
Online Access:	https://hdl.handle.net/10356/104027 http://hdl.handle.net/10220/24635
Tags:	Add Tag No Tags, Be the first to tag this record!
Institution:	Nanyang Technological University
Language:	English

id	sg-ntu-dr.10356-104027
record_format	dspace
spelling	sg-ntu-dr.10356-1040272020-03-07T12:34:56Z β-functionalization of carboxylic anhydrides with β-alkyl substituents through carbene organocatalysis Jin, Zhichao Chen, Shaojin Wang, Yuhuang Zheng, Pengcheng Yang, Song Chi, Robin Yonggui School of Physical and Mathematical Sciences DRNTU::Science::Chemistry::Organic chemistry::Carbanions DRNTU::Science::Chemistry::Physical chemistry::Catalysis The first NHC-catalyzed functionalization of carboxylic anhydrides is described. In this reaction, the β carbon behaves as a nucleophilic carbon and undergoes asymmetric reactions with electrophiles. Anhydrides with challenging β-alkyl substituents work effectively. 2015-01-15T07:45:11Z 2019-12-06T21:24:54Z 2015-01-15T07:45:11Z 2019-12-06T21:24:54Z 2014 2014 Journal Article Jin, Z., Chen, S., Wang, Y., Zheng, P., Yang, S., & Chi, R. Y. (2014). β-functionalization of carboxylic anhydrides with β-alkyl substituents through carbene organocatalysis. Angewandte chemie international edition, 53(49), 13506-13509. 1433-7851 https://hdl.handle.net/10356/104027 http://hdl.handle.net/10220/24635 10.1002/anie.201408604 en Angewandte chemie international edition © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
institution	Nanyang Technological University
building	NTU Library
country	Singapore
collection	DR-NTU
language	English
topic	DRNTU::Science::Chemistry::Organic chemistry::Carbanions DRNTU::Science::Chemistry::Physical chemistry::Catalysis
spellingShingle	DRNTU::Science::Chemistry::Organic chemistry::Carbanions DRNTU::Science::Chemistry::Physical chemistry::Catalysis Jin, Zhichao Chen, Shaojin Wang, Yuhuang Zheng, Pengcheng Yang, Song Chi, Robin Yonggui β-functionalization of carboxylic anhydrides with β-alkyl substituents through carbene organocatalysis
description	The first NHC-catalyzed functionalization of carboxylic anhydrides is described. In this reaction, the β carbon behaves as a nucleophilic carbon and undergoes asymmetric reactions with electrophiles. Anhydrides with challenging β-alkyl substituents work effectively.
author2	School of Physical and Mathematical Sciences
author_facet	School of Physical and Mathematical Sciences Jin, Zhichao Chen, Shaojin Wang, Yuhuang Zheng, Pengcheng Yang, Song Chi, Robin Yonggui
format	Article
author	Jin, Zhichao Chen, Shaojin Wang, Yuhuang Zheng, Pengcheng Yang, Song Chi, Robin Yonggui
author_sort	Jin, Zhichao
title	β-functionalization of carboxylic anhydrides with β-alkyl substituents through carbene organocatalysis
title_short	β-functionalization of carboxylic anhydrides with β-alkyl substituents through carbene organocatalysis
title_full	β-functionalization of carboxylic anhydrides with β-alkyl substituents through carbene organocatalysis
title_fullStr	β-functionalization of carboxylic anhydrides with β-alkyl substituents through carbene organocatalysis
title_full_unstemmed	β-functionalization of carboxylic anhydrides with β-alkyl substituents through carbene organocatalysis
title_sort	β-functionalization of carboxylic anhydrides with β-alkyl substituents through carbene organocatalysis
publishDate	2015
url	https://hdl.handle.net/10356/104027 http://hdl.handle.net/10220/24635
_version_	1681039435148296192

β-functionalization of carboxylic anhydrides with β-alkyl substituents through carbene organocatalysis

Similar Items