Combining single-molecule manipulation and peptide nucleic acid binding studies for unraveling how RNA structures regulate ribosomal frameshifting and alternative splicing
RNA structures are involved in regulating many biological activities such as programmed ribosomal frameshifting and pre-mRNA alternative splicing. Studying the structural features, mechanical stabilities, unfolding and folding dynamics of native RNAs and their mutants, as well as the interaction wit...
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| Format: | Theses and Dissertations |
| Language: | English |
| Published: |
2019
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| Online Access: | https://hdl.handle.net/10356/104424 http://hdl.handle.net/10220/48612 |
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| Institution: | Nanyang Technological University |
| Language: | English |