Overexpression of CDC42SE1 in A431 cells reduced cell proliferation by inhibiting the Akt pathway

Cell division cycle 42 (CDC42), a small Rho GTPase, plays a critical role in many cellular processes, including cell proliferation and survival. CDC42 interacts with the CRIB (Cdc42- and Rac-interactive binding) domain of CDC42SE1, a small effector protein of 9 kDa. We found that the expression of C...

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Bibliographic Details
Main Authors: Kalailingam, Pazhanichamy, Tan, Hui Bing, Pan, Jiun Yit, Tan, Suat Hoon, Thanabalu, Thirumaran
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2019
Subjects:
Online Access:https://hdl.handle.net/10356/104785
http://hdl.handle.net/10220/48621
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Institution: Nanyang Technological University
Language: English