Overexpression of CDC42SE1 in A431 cells reduced cell proliferation by inhibiting the Akt pathway
Cell division cycle 42 (CDC42), a small Rho GTPase, plays a critical role in many cellular processes, including cell proliferation and survival. CDC42 interacts with the CRIB (Cdc42- and Rac-interactive binding) domain of CDC42SE1, a small effector protein of 9 kDa. We found that the expression of C...
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Main Authors: | Kalailingam, Pazhanichamy, Tan, Hui Bing, Pan, Jiun Yit, Tan, Suat Hoon, Thanabalu, Thirumaran |
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Other Authors: | School of Biological Sciences |
Format: | Article |
Language: | English |
Published: |
2019
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/104785 http://hdl.handle.net/10220/48621 |
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Institution: | Nanyang Technological University |
Language: | English |
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