Upconversion nanoparticles as a contrast agent for photoacoustic imaging in live mice

Upconversion nanoparticles as a contrast agent for photoacoustic imaging in live mice

An inclusion complex of NaYF4:Yb3+,Er3+ upconversion nanoparticles with α-cyclodextrin in aqueous conditions exhibits luminescence quenching when excited at 980 nm. This non-radiative relaxation leads to an unprecedented photoacoustic signal enhancement. In vivo localization of α-cyclodextrin-covere...

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Main Authors: Maji, Swarup Kumar, Sreejith, Sivaramapanicker, Joseph, James, Lin, Manjing, He, Tingchao, Tong, Yan, Sun, Handong, Yu, Sidney Wing-Kwong, Zhao, Yanli
其他作者: School of Physical and Mathematical Sciences
格式: Article
語言:English
出版: 2014
主題:
DRNTU::Engineering::Materials
在線閱讀:https://hdl.handle.net/10356/105138
http://hdl.handle.net/10220/20503
http://dx.doi.org/10.1002/adma.201400831
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機構: Nanyang Technological University
語言: English
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總結:An inclusion complex of NaYF4:Yb3+,Er3+ upconversion nanoparticles with α-cyclodextrin in aqueous conditions exhibits luminescence quenching when excited at 980 nm. This non-radiative relaxation leads to an unprecedented photoacoustic signal enhancement. In vivo localization of α-cyclodextrin-covered NaYF4:Yb3+,Er3+ is demonstrated using photoacoustic tomography in live mice, showing its high capability for photoacoustic imaging.

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