Orthogonally engineering matrix topography and rigidity to regulate multicellular morphology

Programmable polymer substrates, which mimic the variable extracellular matrices in living systems, are used to regulate multicellular morphology, via orthogonally modulating the matrix topography and elasticity. The multicellular morphology is dependent on the competition between cell–matrix adhesi...

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Bibliographic Details
Main Authors: Hu, Benhui, Shi, Wenxiong, Wu, Yun-Long, Leow, Wan Ru, Cai, Pingqiang, Li, Shuzhou, Chen, Xiaodong
Other Authors: School of Materials Science & Engineering
Format: Article
Language:English
Published: 2014
Subjects:
Online Access:https://hdl.handle.net/10356/105186
http://hdl.handle.net/10220/20499
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Institution: Nanyang Technological University
Language: English