General suzuki coupling of heteroaryl bromides by using Tri-tert-butylphosphine as a supporting ligand

General suzuki coupling of heteroaryl bromides by using Tri-tert-butylphosphine as a supporting ligand

A general procedure for the fast Suzuki coupling of major families of heteroaryl bromides was realized by using Pd(OAc)2/PtBu3 as the catalyst. Many couplings were finished within minutes at room temperature in n-butanol. Different from previous studies, three typical heteroaryl bromides were system...

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Bibliographic Details
Main Authors: Zou, Yinjun, Yue, Guizhou, Xu, Jianwei, Zhou, Steve Jianrong
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2014
Subjects:
DRNTU::Science::Chemistry::Organic chemistry
Online Access:https://hdl.handle.net/10356/105208
http://hdl.handle.net/10220/20699
http://dx.doi.org/10.1002/ejoc.201402915
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Institution: Nanyang Technological University
Language: English
Description
Summary:A general procedure for the fast Suzuki coupling of major families of heteroaryl bromides was realized by using Pd(OAc)2/PtBu3 as the catalyst. Many couplings were finished within minutes at room temperature in n-butanol. Different from previous studies, three typical heteroaryl bromides were systematically examined in couplings of various heteroaryl and aryl boronic acids.

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