General suzuki coupling of heteroaryl bromides by using Tri-tert-butylphosphine as a supporting ligand

• Main Authors: Zou, Yinjun, Yue, Guizhou, Xu, Jianwei, Zhou, Steve Jianrong
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Science::Chemistry::Organic chemistry
• Online Access: https://hdl.handle.net/10356/105208; http://hdl.handle.net/10220/20699; http://dx.doi.org/10.1002/ejoc.201402915
• Institution: Nanyang Technological University

A general procedure for the fast Suzuki coupling of major families of heteroaryl bromides was realized by using Pd(OAc)2/PtBu3 as the catalyst. Many couplings were finished within minutes at room temperature in n-butanol. Different from previous studies, three typical heteroaryl bromides were system...