Copper-catalyzed asymmetric arylation of N-heteroaryl aldimines : elementary step of a 1,4-insertion

• المؤلفون الرئيسيون: Wu, Chunlin, Qin, Xurong, Moeljadi, Adhitya Mangala Putra, Hirao, Hajime, Zhou, Steve Jianrong
• مؤلفون آخرون: School of Physical and Mathematical Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2021
• الموضوعات: Science::Chemistry; Arylation; Asymmetric Catalysis
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/151793

Copper complexes of monodentate phosphoramidites efficiently promote asymmetric arylation of N-azaaryl aldimines with arylboroxines. DFT calculations and experiments support an elementary step of 1,4-insertion in the reaction pathway, a step in which an aryl-copper species adds directly across four...