Adaptor protein regulation of T-lymphocyte migration

Adaptor protein regulation of T-lymphocyte migration

T-lymphocyte migration is central to the adaptive immune response, which is dependent mainly on the integrin LFA-1-mediated signalling. LFA-1 interacts with its ligand ICAM-1 (expressed on endothelium) and this interaction triggers cytoskeletal rearrangement and T-cell motility. Centrosome and Golgi...

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Main Author: Lim, Carey Fang Hui
Other Authors: Navin Kumar Verma
Format: Student Research Poster
Language:English
Published: 2015
Subjects:
T-lymphocyte
HuT78
Online Access:https://hdl.handle.net/10356/105641
http://hdl.handle.net/10220/25933
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Institution: Nanyang Technological University
Language: English
id sg-ntu-dr.10356-105641
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spelling sg-ntu-dr.10356-1056412020-09-27T20:27:24Z Adaptor protein regulation of T-lymphocyte migration Lim, Carey Fang Hui Navin Kumar Verma Lee Kong Chian School of Medicine (LKCMedicine) T-lymphocyte HuT78 T-lymphocyte migration is central to the adaptive immune response, which is dependent mainly on the integrin LFA-1-mediated signalling. LFA-1 interacts with its ligand ICAM-1 (expressed on endothelium) and this interaction triggers cytoskeletal rearrangement and T-cell motility. Centrosome and Golgi localized Protein Kinase N- Associated Protein (CG-NAP) is an adaptor protein and plays a multifunctional role in facilitating signal transduction processes. However, the mechanistic role of CG-NAP in T-lymphocyte migration is not clear. [4th Award] 2015-06-17T02:47:28Z 2019-12-06T21:55:08Z 2015-06-17T02:47:28Z 2019-12-06T21:55:08Z 2015 2015 Student Research Poster Lim, C. F. H. (2015, March). Adaptor protein regulation of T-lymphocyte migration. Presented at Discover URECA @ NTU poster exhibition and competition, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/105641 http://hdl.handle.net/10220/25933 en © 2015 The Author(s). application/pdf
institution Nanyang Technological University
building NTU Library
country Singapore
collection DR-NTU
language English
topic T-lymphocyte
HuT78
spellingShingle T-lymphocyte
HuT78
Lim, Carey Fang Hui
Adaptor protein regulation of T-lymphocyte migration
description T-lymphocyte migration is central to the adaptive immune response, which is dependent mainly on the integrin LFA-1-mediated signalling. LFA-1 interacts with its ligand ICAM-1 (expressed on endothelium) and this interaction triggers cytoskeletal rearrangement and T-cell motility. Centrosome and Golgi localized Protein Kinase N- Associated Protein (CG-NAP) is an adaptor protein and plays a multifunctional role in facilitating signal transduction processes. However, the mechanistic role of CG-NAP in T-lymphocyte migration is not clear. [4th Award]
author2 Navin Kumar Verma
author_facet Navin Kumar Verma
Lim, Carey Fang Hui
format Student Research Poster
author Lim, Carey Fang Hui
author_sort Lim, Carey Fang Hui
title Adaptor protein regulation of T-lymphocyte migration
title_short Adaptor protein regulation of T-lymphocyte migration
title_full Adaptor protein regulation of T-lymphocyte migration
title_fullStr Adaptor protein regulation of T-lymphocyte migration
title_full_unstemmed Adaptor protein regulation of T-lymphocyte migration
title_sort adaptor protein regulation of t-lymphocyte migration
publishDate 2015
url https://hdl.handle.net/10356/105641
http://hdl.handle.net/10220/25933
_version_ 1681056198503170048

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