Single-cell gene expression analysis reveals β-cell dysfunction and deficit mechanisms in type 2 diabetes
Background: Type 2 diabetes (T2D) is one of the most common chronic diseases. Studies on T2D are mainly built upon bulk-cell data analysis, which measures the average gene expression levels for a population of cells and cannot capture the inter-cell heterogeneity. The single-cell RNA-sequencing tech...
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| Main Authors: | , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2019
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/105665 http://hdl.handle.net/10220/48721 http://dx.doi.org/10.1186/s12859-018-2519-1 |
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| Institution: | Nanyang Technological University |
| Language: | English |