The potential of fluocinolone acetonide to mitigate inflammation and lipid accumulation in 2D and 3D foam cell cultures

• Main Authors: Nguyen, Luong T. H., Muktabar, Aristo, Tang, Jinkai, Wong, Yee Shan, Thaxton, Colby S., Venkatraman, Subbu Subramanian, Ng, Kee Woei
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2019
• Subjects: DRNTU::Engineering::Materials; Lipid Accumulation; Atherosclerosis
• Online Access: https://hdl.handle.net/10356/106089; http://hdl.handle.net/10220/47421
• Institution: Nanyang Technological University

Inflammation plays an important role in all stages of atherosclerosis development. Therefore, the use of anti-inflammatory drugs could reduce the risk of major adverse cardiovascular events due to atherosclerosis. Herein, we explored the capacity of fluocinolone acetonide (FA), a glucocorticoid (GC)...