Presynaptic nanodomains : a tale of two synapses

• المؤلفون الرئيسيون: Wang, Lu-Yang, Augustine, George J.
• مؤلفون آخرون: Lee Kong Chian School of Medicine (LKCMedicine)
• التنسيق: مقال
• اللغة: English
• منشور في: 2015
• الموضوعات: DRNTU::Science::Biological sciences::Human anatomy and physiology::Neurobiology
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/106622; http://hdl.handle.net/10220/25031

Here we summarize the evidence from two “giant” presynaptic terminals—the squid giant synapse and the mammalian calyx of Held—supporting the involvement of nanodomain calcium signals in triggering of neurotransmitter release. At the squid synapse, there are three main lines of experimental evidence...