A neuroprotective role for microRNA miR-1000 mediated by limiting glutamate excitotoxicity

• Main Authors: Verma, Pushpa, Augustine, George James, Ammar, Mohamed-Raafet, Tashiro, Ayumu, Cohen, Stephen M
• 其他作者: Lee Kong Chian School of Medicine (LKCMedicine)
• 格式: Article
• 語言: English
• 出版: 2015
• 主題: DRNTU::Science::Biological sciences::Human anatomy and physiology::Neurobiology
• 在線閱讀: https://hdl.handle.net/10356/107024; http://hdl.handle.net/10220/25258
• 機構: Nanyang Technological University

Evidence has begun to emerge for microRNAs as regulators of synaptic signaling, specifically acting to control postsynaptic responsiveness during synaptic transmission. In this report, we provide evidence that Drosophila melanogaster miR-1000 acts presynaptically to regulate glutamate release at the...