A neuroprotective role for microRNA miR-1000 mediated by limiting glutamate excitotoxicity

• المؤلفون الرئيسيون: Verma, Pushpa, Augustine, George James, Ammar, Mohamed-Raafet, Tashiro, Ayumu, Cohen, Stephen M
• مؤلفون آخرون: Lee Kong Chian School of Medicine (LKCMedicine)
• التنسيق: مقال
• اللغة: English
• منشور في: 2015
• الموضوعات: DRNTU::Science::Biological sciences::Human anatomy and physiology::Neurobiology
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/107024; http://hdl.handle.net/10220/25258
• المؤسسة: Nanyang Technological University

Evidence has begun to emerge for microRNAs as regulators of synaptic signaling, specifically acting to control postsynaptic responsiveness during synaptic transmission. In this report, we provide evidence that Drosophila melanogaster miR-1000 acts presynaptically to regulate glutamate release at the...