Angiopoietin-like 4 stimulates STAT3-mediated iNOS expression and enhances angiogenesis to accelerate wound healing in diabetic mice

• المؤلفون الرئيسيون: Chong, Han Chung, Chan, Jeremy Soon Kiat, Goh, Chi Qin, Gounko, Natalia V., Luo, Baiwen, Wang, Xiaoling, Foo, Selin, Wong, Marcus Thien Chong, Choong, Cleo Swee Neo, Kersten, Sander, Tan, Nguan Soon
• مؤلفون آخرون: School of Materials Science & Engineering
• التنسيق: مقال
• اللغة: English
• منشور في: 2015
• الموضوعات: DRNTU::Science::Biological sciences::Molecular biology
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/106780; http://hdl.handle.net/10220/26002

Impaired wound healing is a major source of morbidity in diabetic patients. Poor outcome has, in part, been related to increased inflammation, poor angiogenesis, and deficiencies in extracellular matrix components. Despite the enormous impact of these chronic wounds, effective therapies are lacking....