The role of fibroblasts in cancer progression, therapy resistance and field cancerization

by Chan, Jeremy Soon Kiat
Published 2017

Targeting nuclear receptors in cancer-associated fibroblasts as concurrent therapy to inhibit development of chemoresistant tumors

by Chan, Jeremy Soon Kiat, Sng, Ming Keat, Teo, Zi Qiang, Chong, Han Chung, Twang, Jing Shun, Tan, Nguan Soon
Published 2019

Conditional knock out of N-WASP in keratinocytes causes skin barrier defects and atopic dermatitis-like inflammation

by Kalailingam, Pazhanichamy, Tan, Hui Bing, Jain, Neeraj, Sng, Ming Keat, Chan, Jeremy Soon Kiat, Tan, Nguan Soon, Thanabalu, Thirumaran
Published 2018

Conditional knockout of N-WASP in mouse fibroblast caused keratinocyte hyper proliferation and enhanced wound closure

by Kalailingam, Pazhanichamy, Tan, Kai Wei, Tan, Hui Bing, Sng, Ming Keat, Chan, Jeremy Soon Kiat, Tan, Nguan Soon, Thanabalu, Thirumaran, Jain, Neeraj
Published 2017

Cancer-associated fibroblasts enact field cancerization by promoting extratumoral oxidative stress

by Li, Liang, Chan, Jeremy Soon Kiat, Tan, Ming Jie, Sng, Ming Keat, Teo, Ziqiang, Phua, Terri, Choo, Chee Chong, Zhu, Pengcheng, Tan, Nguan Soon
Published 2018

ROS release by PPARβ/δ-null fibroblasts reduces tumor load through epithelial antioxidant response

by Tan, Eddie Han Pin, Sng, Ming Keat, How, Ivan Shun Bo, Chan, Jeremy Soon Kiat, Chen, Jiapeng, Tan, Chek Kun, Wahli, Walter, Tan, Nguan Soon
Published 2019

Elevation of adenylate energy charge by angiopoietin-like 4 enhances epithelial–mesenchymal transition by inducing 14-3-3γ expression

by Teo, Ziqiang, Sng, Ming Keat, Chan, Jeremy Soon Kiat, Lim, Maegan Miang Kee, Li, Yinliang, Li, Luchun, Phua, Terri, Lee, J. Y. H., Tan, Zhen Wei, Zhu, Pengcheng, Tan, Nguan Soon
Published 2018

Angiopoietin-like 4 stimulates STAT3-mediated iNOS expression and enhances angiogenesis to accelerate wound healing in diabetic mice

by Chong, Han Chung, Chan, Jeremy Soon Kiat, Goh, Chi Qin, Gounko, Natalia V., Luo, Baiwen, Wang, Xiaoling, Foo, Selin, Wong, Marcus Thien Chong, Choong, Cleo Swee Neo, Kersten, Sander, Tan, Nguan Soon
Published 2015

Angiopoietin-like 4 induces a β-catenin-mediated upregulation of ID3 in fibroblasts to reduce scar collagen expression

by Teo, Ziqiang, Chan, Jeremy Soon Kiat, Chong, Han Chung, Sng, Ming Keat, Choo, Chee Chong, Phua, Glendon Zhi Ming, Teo, Daniel Jin Rong, Zhu, Pengcheng, Choong, Cleo Swee Neo, Wong, Marcus Thien Chong, Tan, Nguan Soon
Published 2018

Angiopoietin-like 4 Mediates Colonic Inflammation by Regulating Chemokine Transcript Stability via Tristetraprolin

by Phua, Terri, Sng, Ming Keat, Tan, Eddie Han Pin, Chee, Dickson Shao Liang, Li, Yinliang, Wee, Jonathan Wei Kiat, Teo, Ziqiang, Chan, Jeremy Soon Kiat, Lim, Maegan Miang Kee, Tan, Chek Kun, Zhu, Pengcheng, Arulampalam, Velmurugesan, Tan, Nguan Soon
Published 2017

Src is activated by the nuclear receptor peroxisome proliferator-activated receptor β/δ in ultraviolet radiation-induced skin cancer

by Chan, Jeremy Soon Kiat, Montagner, Alexandra, Tallichet-Blanc, Corinne, Mottaz, Hélène, Degueurce, Gwendoline, Lippi, Yannick, Moret, Catherine, Baruchet, Michael, Antsiferova, Maria, Werner, Sabine, Hohl, Daniel, Al Saati, Talal, Michalik, Liliane, Wahli, Walter, Delgado, Maria B., Sng, Ming K., Farmer, Pierre J., Tan, Nguan S.
Published 2014

Deficiency in fibroblast PPARβ/δ reduces nonmelanoma skin cancers in mice

by Tan, Mark Wei Yi, Sng, Ming Keat, Cheng, Hong Sheng, Low, Zun Siong, Leong, Benjamin Jia Juin, Chua, Damien, Tan, Eddie Han Pin, Chan, Jeremy Soon Kiat, Yip, Yun Sheng, Lee, Yin Hao, Pal, Mintu, Wang, Xiaomeng, Wahli, Walter, Tan, Nguan Soon
Published 2020

Selective deletion of PPARβ/δ in fibroblasts causes dermal fibrosis by attenuated LRG1 expression

by Sng, Ming Keat, Chan, Jeremy Soon Kiat, Teo, Ziqiang, Phua, Terri, Tan, Eddie Han Pin, Wee, Jonathan Wei Kiat, Koh, Nikki Jun Ning, Tan, Chek Kun, Chen, Jia Peng, Pal, Mintu, Tong, Benny Meng Kiat, Tnay, Ya Lin, Ng, Xuan Rui, Zhu, Pengcheng, Chiba, Shunsuke, Wang, Xiaomeng, Wahli, Walter, Tan, Nguan Soon
Published 2018