Structural features of NS3 of Dengue virus serotypes 2 and 4 in solution and insight into RNA binding and the inhibitory role of quercetin

Dengue virus (DENV), which has four serotypes (DENV‐1 to DENV‐4), is the causative agent of the viral infection dengue. DENV nonstructural protein 3 (NS3) comprises a serine protease domain and an RNA helicase domain which has nucleotide triphosphatase activities that are essential for RNA replicati...

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Bibliographic Details
Main Authors: Manimekalai, Malathy Sony Subramanian, Grüber, Ardina, Joon, Shin, Matsui, Tsutomu, Weiss, Thomas M., Grüber, Gerhard, Pan, Ankita, Saw, Wuan Geok
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2019
Subjects:
Online Access:https://hdl.handle.net/10356/106990
http://hdl.handle.net/10220/49385
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Institution: Nanyang Technological University
Language: English