Discovery of protein complexes with core-attachment structures from tandem affinity purification (TAP) data

• Main Authors: Wu, Min, Li, Xiaoli, Kwoh, Chee Keong, Ng, See-Kiong, Wong, Limsoon
• 其他作者: School of Computer Engineering
• 格式: Article
• 語言: English
• 出版: 2013
• 主題: DRNTU::Engineering::Computer science and engineering::Computer applications
• 在線閱讀: https://hdl.handle.net/10356/107218; http://hdl.handle.net/10220/17736
• 機構: Nanyang Technological University

Many cellular functions involve protein complexes that are formed by multiple interacting proteins. Tandem Affinity Purification (TAP) is a popular experimental method for detecting such multi-protein interactions. However, current computational methods that predict protein complexes from TAP data r...