Discovery of protein complexes with core-attachment structures from tandem affinity purification (TAP) data

• Main Authors: Wu, Min, Li, Xiaoli, Kwoh, Chee Keong, Ng, See-Kiong, Wong, Limsoon
• Other Authors: School of Computer Engineering
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Engineering::Computer science and engineering::Computer applications
• Online Access: https://hdl.handle.net/10356/107218; http://hdl.handle.net/10220/17736
• Institution: Nanyang Technological University

Many cellular functions involve protein complexes that are formed by multiple interacting proteins. Tandem Affinity Purification (TAP) is a popular experimental method for detecting such multi-protein interactions. However, current computational methods that predict protein complexes from TAP data r...