Multilayered siRNA nanoparticles as a delivery system for extended gene silencing effect

• المؤلف الرئيسي: Ng, Alice Jie Ying
• مؤلفون آخرون: Subbu S. Venkatraman
• التنسيق: Thesis-Master by Research
• اللغة: English
• منشور في: Nanyang Technological University 2020
• الموضوعات: Engineering::Materials::Biomaterials; Engineering::Materials::Material testing and characterization
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/137141
• المؤسسة: Nanyang Technological University

At present, various diseases occur without an effective mode of treatment. The production of undesirable proteins leads to the onset of many diseases. For instance, an elevated expression of secreted protein acidic and rich in cysteine (SPARC) is linked with fibrosis and the inhibition of SPARC expr...