Zika virus infection preferentially counterbalances human peripheral monocyte and/or NK cell activity

• Main Authors: Lum, Fok-Moon, Lee, David, Chua, Tze-Kwang, Tan, Jeslin J.L., Lee, Cheryl Y. P., Liu, Xuan, Fang, Yongxiang, Lee, Bernett, Yee, Wearn-Xin, Rickett, Natasha Y., Chia, Po-Ying, Lim, Vanessa, Leo, Yee-Sin, Matthews, David A., Hiscox, Julian A., Ng, Lisa F. P.
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Medicine; NK Cells; RNA-seq
• Online Access: https://hdl.handle.net/10356/137654
• Institution: Nanyang Technological University

Zika virus (ZIKV) has reemerged in the population and caused unprecedented global outbreaks. Here, the transcriptomic consequences of ZIKV infection were studied systematically first in human peripheral blood CD14+ monocytes and monocyte-derived macrophages with high-density RNA sequencing. Analyses...