Light-responsive prodrug-based supramolecular nanosystems for site-specific combination therapy of cancer

• Main Authors: Phua, Fiona Soo Zeng, Xue, Chencheng, Lim, Wei Qi, Yang, Guangbao, Chen, Hongzhong, Zhang, Yuanyuan, Wijaya, Chintya Fransisca, Luo, Zhong, Zhao, Yanli
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Chemistry; Nanomedicine; Light
• Online Access: https://hdl.handle.net/10356/137660
• Institution: Nanyang Technological University

On-demand release of chemotherapeutic drugs from their prodrugs triggered by light irradiation has been attracting great attention for effective cancer treatment. Herein, we prepared prodrug based supramolecular nanoparticles (HA−aPS−aCPT) composed of (1) β-cyclodextrin conjugated hyaluronic acid po...