Amorphous drug-polyelectrolyte nanoparticle complex with controlled release functionality, enhanced amorphous stability, and its continuous production platform

• Main Author: Dong, Bingxue
• Other Authors: Kunn Hadinoto Ong
• Format: Thesis-Doctor of Philosophy
• Language: English
• Published: Nanyang Technological University 2020
• Subjects: Engineering
• Online Access: https://hdl.handle.net/10356/138167
• Institution: Nanyang Technological University

In spite of various contemporary medicinal approaches developed, there are still more than 40% of drugs in the pharmaceutic market and more than 70% of the drug candidates are insoluble in water, resulting in low oral bioavailability and low therapeutic effectivity of the drugs or drug candidates. S...