Amorphous drug-polyelectrolyte nanoparticle complex with controlled release functionality, enhanced amorphous stability, and its continuous production platform
In spite of various contemporary medicinal approaches developed, there are still more than 40% of drugs in the pharmaceutic market and more than 70% of the drug candidates are insoluble in water, resulting in low oral bioavailability and low therapeutic effectivity of the drugs or drug candidates. S...
Saved in:
Main Author: | Dong, Bingxue |
---|---|
Other Authors: | Kunn Hadinoto Ong |
Format: | Thesis-Doctor of Philosophy |
Language: | English |
Published: |
Nanyang Technological University
2020
|
Subjects: | |
Online Access: | https://hdl.handle.net/10356/138167 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Nanyang Technological University |
Language: | English |
Similar Items
-
Carboxymethyl cellulose is a superior polyanion to dextran sulfate in stabilizing and enhancing the solubility of amorphous drug-polyelectrolyte nanoparticle complex
by: Dong, Bingxue, et al.
Published: (2020) -
Enhancing the physical stability and supersaturation generation of amorphous drug-polyelectrolyte nanoparticle complex via incorporation of crystallization inhibitor at the nanoparticle formation step: A case of HPMC versus PVP
by: Dong, Bingxue, et al.
Published: (2020) -
Direct comparison between millifluidic and bulk-mixing platform in the synthesis of amorphous drug-polysaccharide nanoparticle complex
by: Dong, Bingxue, et al.
Published: (2020) -
Self-assembled amorphous drug–polyelectrolyte nanoparticle complex with enhanced dissolution rate and saturation solubility
by: Cheow, Wean Sin, et al.
Published: (2013) -
Amorphous nanoparticle complex of perphenazine and dextran sulfate as a new solubility enhancement strategy of antipsychotic perphenazine
by: Dong, Bingxue, et al.
Published: (2020)