Direct substitution of secondary and tertiary alcohols to generate sulfones under catalyst- and additive-free conditions

• Main Authors: Liu, Yanan, Xie, Peizhong, Sun, Zuolian, Wo, Xiangyang, Gao, Cuiqing, Fu, Weishan, Loh, Teck-Peng
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Chemistry; Sulfones; Alcohols
• Online Access: https://hdl.handle.net/10356/138673
• Institution: Nanyang Technological University

An environmentally benign protocol that affords propargylic sulfones containing highly congested carbon centers from easily accessible alcohols and sulfinic acids with water as the only byproduct is reported. The reaction proceeded via an in situ dehydrative cross-coupling process by taking advantag...