Mechanism of direct C-H arylation of pyridine via a transient activator strategy : a combined computational and experimental study

• المؤلفون الرئيسيون: Jia, Feiyun, Yin, Changzhen, Zeng, Yang, Sun, Rui, Ge, Yi-Cen, Xu, Dingguo, Li, Ruixiang, Chen, Hua, Zhang, Chunchun, Fu, Haiyan
• مؤلفون آخرون: School of Physical and Mathematical Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2020
• الموضوعات: Science::Chemistry; C-h Arylation; Pyridine
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/138887
• المؤسسة: Nanyang Technological University

Recently, we realized the highly selective one-pot synthesis of 2,6-diarylpyridines by using a Pd-catalyzed direct C-H arylation approach via a transient activator strategy. Although methylation reagent as a transient activator and Cu(I) salt or oxide were found to be prerequisites, details regardin...