Mechanism of direct C-H arylation of pyridine via a transient activator strategy : a combined computational and experimental study

• Main Authors: Jia, Feiyun, Yin, Changzhen, Zeng, Yang, Sun, Rui, Ge, Yi-Cen, Xu, Dingguo, Li, Ruixiang, Chen, Hua, Zhang, Chunchun, Fu, Haiyan
• 其他作者: School of Physical and Mathematical Sciences
• 格式: Article
• 語言: English
• 出版: 2020
• 主題: Science::Chemistry; C-h Arylation; Pyridine
• 在線閱讀: https://hdl.handle.net/10356/138887

Recently, we realized the highly selective one-pot synthesis of 2,6-diarylpyridines by using a Pd-catalyzed direct C-H arylation approach via a transient activator strategy. Although methylation reagent as a transient activator and Cu(I) salt or oxide were found to be prerequisites, details regardin...