Palladium-catalyzed regioselective olefination of O-acetyl cyanohydrins

A practical palladium-catalyzed ortho-olefination of O-acetyl cyanohydrins assisted by synergetic directing groups has been developed. Thus, a range of olefinated O-acetyl cyanohydrins were synthesized in moderate to good yields. The reaction occurs efficiently with high regioselectivity and with a...

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Bibliographic Details
Main Authors: Liang, Qiu-Ju, Jiang, Bing, Xu, Yun-He, Loh, Teck-Peng
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2020
Subjects:
Online Access:https://hdl.handle.net/10356/139183
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Institution: Nanyang Technological University
Language: English