Palladium-catalyzed regioselective olefination of O-acetyl cyanohydrins

• Main Authors: Liang, Qiu-Ju, Jiang, Bing, Xu, Yun-He, Loh, Teck-Peng
• 其他作者: School of Physical and Mathematical Sciences
• 格式: Article
• 語言: English
• 出版: 2020
• 主題: Science::Chemistry; Chemical Reactions; Organic Compounds
• 在線閱讀: https://hdl.handle.net/10356/139183

A practical palladium-catalyzed ortho-olefination of O-acetyl cyanohydrins assisted by synergetic directing groups has been developed. Thus, a range of olefinated O-acetyl cyanohydrins were synthesized in moderate to good yields. The reaction occurs efficiently with high regioselectivity and with a...