Indium(III)‐catalyzed hydration and hydroalkoxylation of α,β‐unsaturated ketones in aqueous media

• Main Authors: Yun, Jin-Jin, Zhi, Man-Ling, Shi, Wen-Xiao, Chu, Xue-Qiang, Shen, Zhi-Liang, Loh, Teck-Peng
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Chemistry; Indium; Hydroxylation
• Online Access: https://hdl.handle.net/10356/139332
• Institution: Nanyang Technological University

The hydration of α,β-unsaturated ketones with water proceeded efficiently in the presence of In(OTf)3 (20 mol%) in aqueous media to afford synthetically versatile β-hydroxyketones in moderate to good yields with good functional group compatibility. The method also can be extended to the hydroalkoxyl...