An unprecedented knot‐like G‐quadruplex peripheral motif

• Main Authors: Truong, Thi Hong Anh, Winnerdy, Fernaldo Richtia, Phan, Anh Tuân
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Chemistry; Science::Biological sciences; Base Pairing; DNA
• Online Access: https://hdl.handle.net/10356/140168
• Institution: Nanyang Technological University

A knot‐like G‐quadruplex peripheral structure is formed by a 7‐nt DNA sequence DL7 (TGTTGGT), in which six out of its seven nucleobases participate in compact base‐pairing interactions. Here, the solution NMR structure of a 24‐nt DNA oligonucleotide containing the DL7 sequence shows the interaction...