Molecular basis of converting proteases to ligases

Peptide asparaginyl ligases (PALs) are an unusual subgroup of asparaginyl endopeptidases (AEPs). They share the same protein structure but catalyse different reactions. AEPs hydrolyse the Asx (Asn/Asp)-Xaa bond while PALs ligate them. PALs are the processing enzymes that mediate the backbone cycliza...

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Bibliographic Details
Main Author: Chang, Hong Yi
Other Authors: James P Tam
Format: Final Year Project
Language:English
Published: Nanyang Technological University 2020
Subjects:
Online Access:https://hdl.handle.net/10356/140892
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Institution: Nanyang Technological University
Language: English