Expanding the substrate specificity of peptide asparaginyl ligase

Through amide bond formation, peptide ligases (such as sortase A and subtiligase) introduce specific protein modifications, providing a specific and affordable tool for protein conjugation. Although sortases and subtiligases are capable of site-specific protein conjugations, their slow ligation rea...

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Bibliographic Details
Main Author: Chua, Niying
Other Authors: Julien Lescar
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2023
Subjects:
Online Access:https://hdl.handle.net/10356/168598
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Institution: Nanyang Technological University
Language: English