Phage display engineering of peptide substrates in enhancing ligation efficiency of peptide asparaginyl ligase
OaAEP1b is a peptide asparaginyl ligase (PAL) that recognizes a C-terminal Asx-containing tripeptide motif (Asn/Asp-X-Y) to generate a site-specific Asn-X peptide bond with an incoming peptide. However, it shows weak peptide cyclase activity, as compared to other PALs, particularly butelase-1, the f...
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| Format: | Final Year Project |
| Language: | English |
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Nanyang Technological University
2020
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| Online Access: | https://hdl.handle.net/10356/143301 |
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| Institution: | Nanyang Technological University |
| Language: | English |