Membrane adaptation limitations in Enterococcus faecalis underlie sensitivity and the inability to develop significant resistance to conjugated oligoelectrolytes

• Main Authors: Chilambi, Gayatri Shankar, Gao, Iris H., Yoon, Bo Kyeong, Park, Soohyun, Kawakami, Lisa M., Ravikumar, Vikashini, Chan-Park, Mary Beeeng, Cho, Nam-Joon, Bazan, Guillermo C., Kline, Kimberly A., Rice, Scott Alan, Hinks, Jamie
• 其他作者: School of Chemical and Biomedical Engineering
• 格式: Article
• 語言: English
• 出版: 2020
• 主題: Engineering::Materials; Enterococcus Faecalis; Oligoelectrolytes
• 在線閱讀: https://hdl.handle.net/10356/141096
• 機構: Nanyang Technological University

The growing problem of antibiotic resistant bacteria, along with a dearth of new antibiotics, has redirected attention to the search for alternative antimicrobial agents. Conjugated oligoelectrolytes (COEs) are an emerging class of antimicrobial agents which insert into bacterial cell membranes and...