Membrane curvature sensing of the lipid-anchored K-Ras small GTPase

• Main Authors: Liang, Hong, Mu, Huanwen, Jean-Francois, Frantz, Lakshman, Bindu, Sarkar-Banerjee, Suparna, Zhuang, Yinyin, Zeng, Yongpeng, Gao, Weibo, Zaske, Ana Maria, Nissley, Dwight V., Gorfe, Alemayehu A., Zhao, Wenting, Zhou, Yong
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2020
• Subjects: Engineering::Bioengineering; Plasma Membrane (PM) Curvature; GTPase
• Online Access: https://hdl.handle.net/10356/141949
• Institution: Nanyang Technological University

Plasma membrane (PM) curvature defines cell shape and intracellular organelle morphologies and is a fundamental cell property. Growth/proliferation is more stimulated in flatter cells than the same cells in elongated shapes. PM-anchored K-Ras small GTPase regulates cell growth/proliferation and play...