Fatty acid metabolism driven mitochondrial bioenergetics promotes advanced developmental phenotypes in human induced pluripotent stem cell derived cardiomyocytes

Fatty acid metabolism driven mitochondrial bioenergetics promotes advanced developmental phenotypes in human induced pluripotent stem cell derived cardiomyocytes

Background: Preferential utilization of fatty acids for ATP production represents an advanced metabolic phenotype in developing cardiomyocytes. We investigated whether this phenotype could be attained in human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) and assessed its influenc...

Full description

Saved in:
Bibliographic Details
Main Authors: Ramachandra, Chrishan J. A., Mehta, Ashish, Wong, Philip, Ja, K. P. Myu Mai, Fritsche-Danielson, Regina, Bhat, Ratan V., Hausenloy, Derek J., Kovalik, Jean-Paul, Shim, Winston
Other Authors: School of Materials Science and Engineering
Format: Article
Language:English
Published: 2020
Subjects:
Engineering::Materials
Mitochondria
Metabolism
Online Access:https://hdl.handle.net/10356/142041
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/142041

Similar Items