Fatty acid metabolism driven mitochondrial bioenergetics promotes advanced developmental phenotypes in human induced pluripotent stem cell derived cardiomyocytes

Fatty acid metabolism driven mitochondrial bioenergetics promotes advanced developmental phenotypes in human induced pluripotent stem cell derived cardiomyocytes

Background: Preferential utilization of fatty acids for ATP production represents an advanced metabolic phenotype in developing cardiomyocytes. We investigated whether this phenotype could be attained in human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) and assessed its influenc...

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Main Authors: Ramachandra, Chrishan J. A., Mehta, Ashish, Wong, Philip, Ja, K. P. Myu Mai, Fritsche-Danielson, Regina, Bhat, Ratan V., Hausenloy, Derek J., Kovalik, Jean-Paul, Shim, Winston
其他作者: School of Materials Science and Engineering
格式: Article
語言:English
出版: 2020
主題:
Engineering::Materials
Mitochondria
Metabolism
在線閱讀:https://hdl.handle.net/10356/142041
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機構: Nanyang Technological University
語言: English

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https://hdl.handle.net/10356/142041

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