Translational assessment of a genetic engineering methodology to improve islet function for transplantation

• Main Authors: van Krieken, Pim P., Voznesenskaya, Anna, Dicker, Andrea, Xiong, Yan, Park, Jae Hong, Lee, Jeong Ik, Ilegems, Erwin, Berggren, Per-Olof
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Medicine; Diabetes; In Vivo Imaging
• Online Access: https://hdl.handle.net/10356/142343
• Institution: Nanyang Technological University

Background: The functional quality of insulin-secreting islet beta cells is a major factor determining the outcome of clinical transplantations for diabetes. It is therefore of importance to develop methodological strategies aiming at optimizing islet cell function prior to transplantation. In this...