Atomic structure and enzymatic insights into the vancomycin-resistant Enterococcus faecalis (V583) alkylhydroperoxide reductase subunit C

• Main Authors: Pan, Ankita, Balakrishna, Asha Manikkoth, Nartey, Wilson, Kohlmeier, Andreas, Dip, Phat Vinh, Bhushan, Shashi, Grüber, Gerhard
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Biological sciences; Oxidative Stress; Reactive Oxygen Species
• Online Access: https://hdl.handle.net/10356/142463
• Institution: Nanyang Technological University

The Enterococcus faecalis alkyl hydroperoxide reductase complex (AhpR) with its subunits AhpC (EfAhpC) and AhpF (EfAhpF) are of paramount importance to restore redox homeostasis. Recently, the novel phenomenon of swapping of the catalytic domains of EfAhpF was uncovered. Here, we visualized its coun...